Indirect calorimetry (IC)-guided nutrition might positively affect the clinical outcome of critically ill patients. The objective of this study is to assess the benefit of isocaloric nutrition guided by IC, compared to hypocaloric nutrition, for critically ill patients admitted to the intensive care unit (ICU). This systematic review and meta-analysis shows that patients treated with IC guided...
COVID-19 can rapidly progress into acute respiratory distress syndrome accompanied by multi-organ failure requiring invasive mechanical ventilation and critical care treatment. Nutritional therapy is a fundamental pillar in the management of hospitalized patients. It is broadly acknowledged that overfeeding and underfeeding of intensive care unit (ICU) patients are associated with increased...
Among other important risk factors for severe COVID-19 outcomes, obesity has emerged along with undernutrition-malnutrition as a strong predictor of disease risk and severity. Obesity-related excessive body fat may lead to respiratory, metabolic and immune derangements potentially favouring the onset of COVID-19 complications. Early after the onset of the COVID-19 pandemic, the European...
Indirect calorimetry (IC) is the gold-standard for determining measured resting energy expenditure (mREE) in critical illness. When IC is not available, predicted resting energy expenditure (pREE) equations are commonly utilized, which often inaccurately predict metabolic demands leading to over- or under-feeding. This study aims to longitudinally assess mREE via IC in critically ill patients...
Critical illness demands objective, targeted nutritional therapy to prevent adverse effects of underfeeding/ over feeding. Thus, all recent societal guidelines recommend indirect calorimetry use to determine energy needs. Current commercially available indirect calorimeters are often inaccurate, and the inconveniences have led to significant challenges to routine indirect calorimetry use in...
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